Factory Supply of Slu-PP-332 CAS 303760-60-3 for Weight Loss Nutrition and Anti-Aging

• Customization: Available
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Model NO.: 303760-60-3
• Quality: Industrial
• Colour: White
• Density: 1.20 g/cm3(Predicted)
• Storage: 2-8 Celsius Degree
• Solubility: 2ml/Ml in DMSO
• Pka: 8.44
• Transport Package: as Required
• Specification: 99%+
• Trademark: Worldyang
• Origin: China

Product Description

Product Name: SLU-PP-332
CAS No.: 303760-60-3
Appearance: White to off-white powder
Purity: 99%
Specifications: ISO 9001:2015 certified

 

Description:

SLU-PP-332, chemically known as 4-Hydroxy-N'-(naphthalen-2-ylmethylene)benzohydrazide, is a potent pan-agonist of the estrogen receptor-related receptors (ERRα, ERRβ, ERRγ). It exhibits high binding affinity with EC50 values of 98 nM (ERRα), 230 nM (ERRβ), and 430 nM (ERRγ). This compound is designed to enhance mitochondrial function, cellular respiration, and oxidative skeletal muscle activity, making it a valuable tool for metabolic and aging-related research.

 

Chemical Properties:

• Molecular Formula: C₁₈H₁₄N₂O₂

• Molecular Weight: 298.32 g/mol

• Density: 1.20 ± 0.1 g/cm³ (Predicted)

• Solubility: Soluble in DMSO (2 mg/mL, clear upon warming).

• pKa: 8.44 ± 0.15 (Predicted)

Applications:

1. Metabolic Disease Research:

   • Enhances mitochondrial function and cellular respiration, offering potential therapeutic strategies for metabolic disorders.

   • Promotes oxidative metabolism in type IIa skeletal muscle fibers, improving exercise tolerance and muscle performance.

2. Aging and Muscle Function:

   • Targets age-related decline in mitochondrial efficiency and muscle atrophy.

   • Supports research on interventions to counteract sarcopenia and frailty.

3. ERR Receptor Studies:

   • Acts as a selective agonist for ERRα, ERRβ, and ERRγ, enabling mechanistic studies of ERR signaling pathways.

 

Functional Highlights:

• Mitochondrial Activation: Boosts energy production and oxidative capacity in cells.

• Muscle Adaptation: Enhances endurance and functional performance in skeletal muscle cell models.

• Metabolic Regulation: Addresses metabolic imbalances linked to obesity, diabetes, and aging.

 

Storage & Handling:

• Storage Conditions: 2-8°C in a dry, light-protected environment.

• Form: Solid powder.

• Shelf Life: 24 months under recommended storage.

 

Quality Assurance:

• Purity: ≥99% (HPLC).

• Impurity Profile: Meets ISO 9001 standards for research-grade compounds.

 

Note: SLU-PP-332 is a cutting-edge compound for advancing research in metabolism, muscle physiology, and aging. Its unique mechanism of action and high specificity make it an indispensable tool for preclinical studies.

For detailed protocols, bulk inquiries, or custom formulations, contact our scientific support team.