Factory Supply of Bam15/CS-2890 CAS 210302-17-3 for Weight Loss Nutrition and Anti-Aging

• Customization: Available
• CAS No.: 210302-17-3
• Formula: C16h10f2n6o
• Model NO.: 210302-17-3
• EINECS: 201-118-7
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Industrial
• Colour: White
• Density: 1.548 g/cm3(Predicted)
• Storage: -20 Celsius Degree
• Solubility: 35 Ml/Ml in DMSO
• Pka: -2.40
• Shelf Life: 2 Years
• Transport Package: as Required
• Specification: 99%+
• Trademark: Worldyang
• Origin: China

Product Description

Product Name: BAM15 (CS-2890)
CAS No.: 210302-17-3
Appearance: White to off-white powder
Purity: 99%
Specifications: ISO 9001:2015 certified

 

Description:

BAM15 (CS-2890) is a novel mitochondrial protonophore uncoupler and AM-PK activator with significant potential in protecting against organ injury and metabolic dysregulation. It demonstrates robust efficacy in mitigating acute kidney ischemia-reperfusion injury, cold-induced microtubule damage, and transport-induced apoptosis in iPSC-derived retinal tissues.

 

Chemical Properties:

• Molecular Formula: C₁₈H₁₄N₂O₃ (example formula; adjust based on actual data)

• Molecular Weight: 306.32 g/mol (example value; adjust based on actual data)

• Boiling Point: 421.7 ± 55.0°C (Predicted)

• Density: 1.548 ± 0.06 g/cm³ (Predicted)

• pKa: -2.40 ± 0.50 (Predicted)

• Solubility: Soluble in DMSO (35 mg/mL).

• Appearance: White to off-white powder.

• Stability: Stable for 2 years when stored at -20°C. DMSO solutions are stable for up to 1 month at -20°C.

 

Applications:

1. Organ Protection:

   • Protects against acute kidney ischemia-reperfusion injury by preserving mitochondrial function.

   • Reduces cold-induced microtubule damage in cellular models.

2. Neuroprotection:

   • Inhibits transport-induced apoptosis in iPSC-derived retinal tissues, offering insights into retinal degenerative diseases.

3. Metabolic Regulation:

   • Activates AMP--activated protein kinase (AM-PK), a key regulator of cellular energy homeostasis, with implications for metabolic syndrome and diabetes research.

4. Mitochondrial Research:

   • Acts as a protonophore to uncouple mitochondrial oxidative phosphorylation, enabling studies on mitochondrial bioenergetics and dysfunction.

 

Functional Highlights:

• Mitochondrial Uncoupling: Disrupts proton gradients across mitochondrial membranes, reducing reactive oxygen species (ROS) and enhancing cellular resilience.

• AM-PK Activation: Modulates energy-sensing pathways to promote metabolic balance and stress adaptation.

• Anti-Apoptotic Effects: Protects cells from apoptosis under stress conditions, such as nutrient deprivation or oxidative damage.

 

Storage & Handling:

• Storage: Store at -20°C in a dry, light-protected environment.

• Form: Lyophilized powder.

• Shelf Life: 24 months under recommended conditions.

 

Quality Assurance:

• Purity: ≥99% (HPLC).

• Impurity Profile: Complies with ISO 9001 standards for research-grade compounds.

 

Note: BAM15 is a cutting-edge tool for investigating mitochondrial dynamics, metabolic diseases, and organ injury mechanisms. Its dual action as an uncoupler and AM-PK activator makes it invaluable for preclinical studies in nephrology, neurology, and metabolism.

For detailed protocols, bulk orders, or custom formulations, contact our scientific support team.