Customization: | Available |
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CAS No.: | 56553-60-7 |
Formula: | C6h10bnao6 |
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Application | Sodium triacetoxyborohydride is a mild reagent that exhibits remarkable selectivity as a reducing agent. It reduces aldehydes but not ketones; however, beta-hydroxyketones can be reduced selectively to give 1,3-trans diols.The steric and the electron-withdrawing effects of the three acetoxy groups stabilize the boron-hydrogen bond and are responsible for its mild reducing properties. Sodium triacetoxyborohydride or [NaBH(OAc)3] can be used as a reagent: In the reductive amination of ketones and aldehydes. To prepare N-benzyl-γ-valerolactam by reacting with methyl 4-oxopentanoate and benzylamine via reductive amination/lactamization. To reduce imines and enamines to corresponding amines. To reduce quinolines and isoquinolines to corresponding tetrahydro derivatives. In the hydroboration of alkenes. To synthesize nitroxide biradicals for creating high relaxivity terminal groups linkage to dendrimers. |