Factory High Quality Tacrolimus CAS 104987-11-3

• Customization: Available
• CAS No.: 104987-11-3
• Formula: C44h69no12
• Model NO.: 104987-11-3
• EINECS: 1308068-626-2
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Industrial
• Colour: White
• Transport Package: as Demanded
• Specification: USP-40
• Trademark: Worldyang
• Origin: China
• HS Code: 2941909099
• Production Capacity: 1000kg/Year

Product Description

Shanghai Worldyang chemical Co., Ltd is a high-tech enterprise focused on industry of fine chemicals research and develop, produce and sale. Shanghai Worldyang chemical Co., Ltd is located in Shanghai China. we have the ability to provide you high quality products. More than 90 % of our products are exported to developed countries and regions such as north America, Europe, Japan, South Korea and the Middle East.

Products are widely used in pesticides, plastics, cosmetics, spices fragrance, water treatment, environmental protection, electronic chemicals and other fields. Up to now, we have established manufacturing bases in Anhui, jiangsu and guangdong separately, at the same time, we build closely cooperative relationship with the well-known universities and institutions of China to research new products constantly.

In addition, we also provide customized services for chemicals and organ silicon for customers around the world. Up the tonnage level down to the gram level can be provided to meet the different needs of our customers. We are good at a variety of reactions, including halogen exchange fluorination, halogenation, nitration, diazotization, grignard and reduction.
 

Product Description

Tacroliums
CAS: 104987-11-3
Certifications: ISO 9001:2015; GMP
Specs:USP-40
Appearance: White Powder

Description
Tacrolimus is an important anti rejection drug for organ transplantation, with efficacy 10-100 times that of cyclosporine. It also has good therapeutic effects on immune diseases such as rheumatoid arthritis and lupus erythematosus.

Clinical Applications
Compared with cyclosporine, the use of tacrolimus has completely changed the future of kidney transplantation because it has higher transplant survival rates, higher drug tolerance, lower rejection rates, and fewer side effects. KDIGO recommended tacrolimus as a first-line CNI for renal transplantation in 2009, as an initial and long-term maintenance immunosuppressive therapy. However, the monitoring of tacrolimus concentration is still complex. Insufficient dosage will increase the risk of rejection, while excessive dosage will increase the risk of side effects, mainly nephrotoxicity, neurotoxicity, infection, malignant tumor, diabetes and gastrointestinal discomfort.

Our research
The research team used synthetic biology technology to reconstruct the production bacteria and fermentation process for precise optimization, and obtained high-yield and stable production bacteria; The separation and purification process has been restructured, and impurities of homologous substances have been basically eliminated. The total impurities of the raw material are far below 1.0%, meeting the USP-40 standard. The project has been granted multiple domestic and foreign invention patents and has independent intellectual property rights.

Name	Tacrolimus
CAS Number	104987-11-3
Standard	USP-40
Package	1kg/drum, 25kg/drum and as demanded