| Customization: | Available |
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| CAS No.: | 56-12-2 |
| Formula: | C4h9no2 |
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Product Name: 4-Aminobutyric Acid (γ-Aminobutyric Acid, GABA)
CAS No.: 56-12-2
Appearance: White powder
Purity: 98%
Specifications: ISO 9001:2015 certified
Description:
4-Aminobutyric Acid, commonly known as γ-Aminobutyric Acid (GABA), is a naturally occurring non-protein amino acid widely distributed in plants and animals. In plants, GABA is found in seeds, roots, and tissues of legumes, ginseng, and various medicinal herbs. In animals, GABA is primarily concentrated in the nervous system, particularly in the brain, where it plays a crucial role as an inhibitory neurotransmitter.
Physiological Functions:
Neurotransmitter Activity:
GABA is the primary inhibitory neurotransmitter in the central nervous system, regulating neuronal excitability and maintaining the balance between excitation and inhibition.
It binds to GABA receptors, which are chloride ion channels, leading to hyperpolarization of neurons and reduced neuronal activity.
Sedative and Hypnotic Effects:
GABA promotes relaxation, reduces anxiety, and improves sleep quality by calming overactive neurons.
Anticonvulsant Properties:
GABA helps prevent seizures by inhibiting excessive neuronal firing.
Blood Pressure Regulation:
GABA has been shown to lower blood pressure by relaxing blood vessels and reducing stress responses.
Metabolic and Cognitive Benefits:
GABA supports brain metabolism and has been linked to improved cognitive function and memory.
Applications:
Medical Use:
Hepatic Encephalopathy: GABA is used to treat liver coma and other conditions caused by elevated blood NH3 levels.
Neurological Disorders: Effective in managing cerebral vascular disorders, stroke sequelae, cerebral arteriosclerosis, and head trauma.
Detoxification: Acts as an antidote for CO poisoning and uremia-induced coma.
Pharmaceutical Intermediate:
GABA serves as a key intermediate in the synthesis of various drugs targeting neurological and metabolic disorders.
Biochemical Research:
Widely used in neuroscience research to study inhibitory neurotransmission and neuronal function.
Nutritional Supplements:
Incorporated into dietary supplements for its calming and stress-relieving effects.
Chemical Properties:
Chemical Name: 4-Aminobutyric Acid (γ-Aminobutyric Acid).
Molecular Formula: C4H9NO2.
Molecular Weight: 103.12 g/mol.
Appearance: White crystalline powder.
Solubility: Soluble in water; slightly soluble in ethanol.
Usage:
Medical Treatment: Administered to manage hepatic coma, neurological disorders, and detoxification.
Research: Used in biochemical and neurological studies.
Nutritional Supplements: Consumed for its calming and cognitive-enhancing effects.
Packaging & Storage:
Store in a cool, dry place, protected from light and moisture.
Shelf life: 24 months under proper storage conditions.
Note: GABA is a vital compound with significant applications in medicine, research, and nutrition. Its role as an inhibitory neurotransmitter and its wide-ranging physiological effects make it a valuable ingredient for promoting neurological health and overall well-being.
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