| Customization: | Available |
|---|---|
| CAS No.: | 99-50-3 |
| Formula: | C7h6o4 |
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Product Name: Protocatechuic Acid (PCA)
CAS No.: 99-50-3
Appearance: White powder
Purity: 98%
Specifications: ISO 9001:2015 certified
Description:
Protocatechuic Acid (PCA), also known as 3,4-dihydroxybenzoic acid, is a simple phenolic acid widely found in edible vegetables, fruits, nuts, brown rice, pecans, tea, hibiscus flowers, and certain traditional Chinese herbs. It serves as a precursor for synthesizing complex molecules such as anthocyanin 3-O-β-D-glucoside and vanillin. PCA is recognized for its diverse biological activities and potential health benefits.
Key Applications and Benefits:
Antioxidant Properties:
PCA exhibits strong antioxidant activity, helping to neutralize free radicals and reduce oxidative stress, which is beneficial for overall health and disease prevention.
Anti-Inflammatory Effects:
PCA has been shown to reduce inflammation by modulating inflammatory pathways, making it useful in managing inflammatory conditions.
Antimicrobial Activity:
PCA demonstrates broad-spectrum antimicrobial properties, effective against various bacteria and pathogens.
Antidiabetic Potential:
PCA helps regulate blood glucose levels, offering potential benefits for managing diabetes and related metabolic disorders.
Neuroprotective Effects:
PCA protects neuronal cells from damage, showing promise in the prevention and treatment of neurodegenerative diseases.
Chemopreventive and Anticancer Properties:
PCA inhibits chemical carcinogens and induces apoptosis (programmed cell death) in cancer cells, making it a potential candidate for cancer prevention and therapy.
Clinical Applications:
PCA is used in the treatment of burns, pediatric pneumonia, bacterial dysentery, acute pyelonephritis, acute pancreatitis, and certain ulcerative conditions.
Chemical Properties:
Appearance: White to light brown needle-like crystals.
Melting Point: Approximately 200°C (with decomposition).
Solubility: Soluble in hot water, ethanol, and ether; slightly soluble in cold water; insoluble in benzene.
Reactivity: Decomposes in boiling water, releasing carbon dioxide.
Color Reactions:
Turns green upon reaction with FeCl3.
Turns dark red upon reaction with sodium bicarbonate (NaHCO3).
Pharmacological Effects:
PCA is a metabolite of complex polyphenols such as anthocyanins and proanthocyanidins, which are abundant in plants and fruits.
It is absorbed by humans and animals, with daily intake of anthocyanins being higher than other polyphenols, highlighting its nutritional value.
Extensive research confirms PCA's diverse biological activities, including antimicrobial, antioxidant, anti-inflammatory, antidiabetic, and neuroprotective effects.
Usage:
Nutritional Supplements: Incorporated into dietary supplements for its antioxidant and health-promoting properties.
Pharmaceuticals: Used in formulations for treating inflammatory, infectious, and metabolic diseases.
Cosmetics: Added to skincare products for its antioxidant and anti-aging benefits.
Packaging & Storage:
Store in a cool, dry place, protected from light and moisture.
Shelf life: 24 months under proper storage conditions.
Note: Protocatechuic Acid is a versatile compound with significant potential in healthcare, nutrition, and disease prevention. Its multifaceted biological activities make it a valuable ingredient in pharmaceuticals, supplements, and cosmetic products.
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